![]() No statistically significant differences in HbA1c were seen between any two insulins or formulations. Of 2534 citations reviewed, 70 studies met the inclusion criteria. ![]() ![]() Meta-analysis was used to combine results of similar studies, and the I 2 statistic calculated to assess statistical heterogeneity. Comparative studies of adult or paediatric patients with diabetes treated with insulin degludec, detemir or glargine were included. Two authors selected studies meeting inclusion criteria and assessed their quality. MEDLINE and two Cochrane databases were searched during February 2018. To review evidence comparing benefits and harms of long-acting insulins in patients with type 1 and 2 diabetes.
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